On the date of April 6th, 1520, Raphael’s 37th birthday, he died. Raphael died an un-expected death of mysterious causes in Rome, Italy. During the time of his death he had been working on his largest painting on canvas, The Transfiguration (Which was finally commissioned in 1517.) No one did ever find out how he died, however Raphael still inspired people for decades because of his wonderful work and dedication.